Overview and Approach

At Juul Labs, scientific research is vitally important, and we are working to expand the body of knowledge around ENDS products, which we believe play a critical role in transitioning adult smokers from combustible cigarettes. We strive to ask the relevant questions and take direction on what research to conduct from regulators and other public-health stakeholders.

We are conducting studies that span nonclinical, clinical, behavioral, and population health areas of investigation with the goal of better understanding the harm-reduction potential of the JUUL System, including their impact on the individual user, their ability to transition adult smokers away from combustible cigarettes, and the net-population impact on public health.

We value scientific exchange and sharing our findings with members of the scientific community. We share the results of our studies with regulators and the public health community through peer-reviewed journals, conference presentations, one-on-one meetings, and this website, which is designed to serve as a centralized portal for Juul Labs to disseminate scientific information to members of the scientific and public health communities, regulators, and policymakers.

More than 100,000 participants to date enrolled in our behavioral studies around the world

More than 110 studies completed or ongoing

14 clinical studies completed

Explore our areas of research

  • Nonclinical studies

    Product and ingredient testing

    Our nonclinical research examines the JUUL System e-liquid and aerosol through various analytical, chemistry, and toxicological assessments in laboratory settings. This includes measuring and evaluating the levels of harmful and potentially harmful constituents (HPHCs) found in the smoke of combustible cigarettes — as outlined by the FDA — compared to the aerosol of the JUUL System.

    See nonclinical studies
  • Clinical studies

    Examining the impact on human health

    Our clinical studies examine the impact of the JUUL System on human health, including the rate and level of nicotine absorption in the body, product use and puff topography, potential secondhand aerosol exposure in real world settings, and reductions in exposure to chemicals tied to harm. These studies assess the physiological impact on adult smokers and the environmental impact on others by examining the level of exposure to a specific substance and potential harm over time with the JUUL System compared to combustible cigarettes.

    See clinical studies
  • Behavioral studies

    What adult smokers do in the real world

    Behavioral factors are critical to understanding the population health impact of the JUUL System among current tobacco product users and nonusers. We have developed an extensive behavioral research program that includes assessments of JUUL System purchasers and general population samples. Epidemiological surveys track patterns of tobacco product use among adult JUUL System users, including their prior cigarette smoking history.

    These assessments included measurements of complete switching from combustible cigarettes to the JUUL System and, for adult smokers that are still transitioning from combustible use, reductions in the number of cigarettes consumed. We also assess perceptions of the potential risks associated with the use of the JUUL System and other tobacco products among both users and nonusers.

    Within our behavioral research program, data on over 100,000 adult survey participants has been collected and analyzed.

    See behavioral studies
  • Economics and Policy Impact studies

    Net population impact, health economics and policy research

    Through our economics and policy impact research, we build causal inference, econometric, and statistical models that demonstrate the impact of ENDS product use, including the JUUL System, on a wide range of key population-level outcomes.

    This includes evaluating the impact of proposed and implemented policies and interventions such as enhanced access controls, Tobacco 21, and bans on ENDS products to understand how they impact ENDS use and/or cigarette sales.

    See economics and policy impact studies